[Addressing the controversy regarding the association between thimerosal-containing vaccines and autism].
نویسندگان
چکیده
Vaccination is one of the most important public health interventions in the reduction childhood morbidity and mortality. Thimerosal is an organic mercury compound used as preservante in multi-dose vials. Often in Peru, there are waves of controversy about the safety of this type of vaccines, mainly arguing that there is an association between them and autism. As a result of these controversies, there have been some voices asking for laws banning thimerosal-containing vaccines, which would have a large impact in costs and the logistic aspects of the public vaccination programs. The aim of this article is to review the literature for the main controversies about thimerosal in vaccines and its supposed association to autism. We made an historical review about these controversies given the available scientific evidence and the statements from important international organizations. We concluded that the current available evidence do not support an association between thimerosal and childhood neurodevelopmental disorders, such as autism.
منابع مشابه
Mercury, vaccines, and autism: one controversy, three histories.
The controversy regarding the once widely used mercury-containing preservative thimerosal in childhood vaccines has raised many historical questions that have not been adequately explored. Why was this preservative incorporated in the first place? Was there any real evidence that it caused harm? And how did thimerosal become linked in the public mind to the "autism epidemic"? I examine the orig...
متن کاملThimerosal-containing vaccines and autistic spectrum disorder: a critical review of published original data.
OBJECTIVE The issue of thimerosal-containing vaccines as a possible cause of autistic spectrum disorders (ASD) and neurodevelopmental disorders (NDDs) has been a controversial topic since 1999. Although most practitioners are familiar with the controversy, many are not familiar with the type or quality of evidence in published articles that have addressed this issue. To assess the quality of ev...
متن کاملBRIEF REPORT Association Between Thimerosal-Containing Vaccine and Autism
HIGH DOSES OF MERCURIC COMpounds are nephrotoxic and neurotoxic. Thimerosal, an organic compound that contains ethylmercury, has been widely used since the 1930s as a preservative in certain vaccines. In the 1990s, an increasing number of different vaccines containing thimerosal were introduced in immunization schedules around the world, and thus the average cumulative exposure to thimerosal in...
متن کاملAutism and thimerosal-containing vaccines: lack of consistent evidence for an association.
BACKGROUND In 1999, concerns were raised that vaccines containing the preservative Thimerosal might increase the risk of autism and/or other neurodevelopmental disorders. METHODS Between the mid-1980s through the late-1990s, we compared the prevalence/incidence of autism in California, Sweden, and Denmark with average exposures to Thimerosal-containing vaccines. Graphic ecologic analyses were...
متن کاملVaccines and autism: evidence does not support a causal association.
A suggested association between certain childhood vaccines and autism has been one of the most contentious vaccine safety controversies in recent years. Despite compelling scientific evidence against a causal association, many parents and parent advocacy groups continue to suspect that vaccines, particularly measles-mumps-rubella (MMR) vaccine and thimerosal-containing vaccines (TCVs), can caus...
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عنوان ژورنال:
- Revista peruana de medicina experimental y salud publica
دوره 30 2 شماره
صفحات -
تاریخ انتشار 2013